Description
GenVoy-ILM™ T Cell Kit for mRNA, Ignite (3 mL and 6 mL) is an off-the-shelf lipid nanoparticle (LNP) reagent mix optimized for the delivery of messenger RNA (mRNA) or Cas9 mRNA/sgRNA into activated human primary T cells. LNPs are prepared on the NanoAssemblr® Ignite™ instrument with Ignite NxGen™ cartridges. This non-viral delivery method can be seamlessly integrated into any standard human T cell culture workflows using an established protocol with either freshly isolated or cryopreserved T cells.
GenVoy-ILM T Cell Kit for mRNA, Ignite enables researchers to establish a clinically relevant and scalable method at the preclinical scale for ex vivo gene delivery and editing to accelerate the development of T cell therapies. This kit is also available as GenVoy-ILM™ T Cell Kit for mRNA, Spark for LNPs prepared on NanoAssemblr Spark™.
Features:
Highly Efficient Knockout and Expression - Deliver mRNA or mRNA/sgRNA into activated primary T cells consistently with high efficiency.
High Cell Viability - Maintain high T cell viability, even after multi-step cell engineering.
Scalable from Discovery to Preclinical - Scale your cell therapy research on the NanoAssemblr® platform.
Validated with T cell Manufacturing Workflow - Optimized and validated for downstream T cell culture workflow.
Move to the Clinic with Minimum Hurdles - Accelerate your cell therapy research with this off-the-shelf LNP reagent with a path to the clinic